PIB

Amyloid Burden and White Matter Hyperintensities Mediate Age-Related Cognitive Differences

In this cross-sectional study, we have sought to examine the additive vs synergistic contribution of beta-amyloid (Aβ) and white matter hyperintensities (WMH) across seven cognitive domains in 104 cognitively normal elderly individuals. A primary …

Education as a moderator of the relationship between episodic memory and amyloid load in normal aging

The current study explored whether education, a proxy of cognitive reserve, modifies the association between episodic memory performance and βeta-amyloid load (Aβ), a biomarker of Alzheimer’s disease, in a cohort of cognitively normal elderly adults. …