Aging

Executive deficits in schizophrenia: Mediation by processing speed and its relationships with aging

**Background**: Executive deficits are a core characteristic of schizophrenia. Yet, the origin of these impairments remains unclear as they may be caused by processing slowing. This issue is of particular interest for aging insofar as cognitive aging …

Amyloid burden and white matter hyperintensities mediate age related cognitive differences

In this cross-sectional study, we have sought to examine the additive vs synergistic contribution of beta-amyloid (Aβ) and white matter hyperintensities (WMH) across seven cognitive domains in 104 cognitively normal elderly individuals. A primary …

Executive functions in schizophrenia aging: differential effects of age within specific executive functions

There are common cognitive and brain abnormalities in schizophrenia and healthy aging which may cumulate in schizophrenia aging. However, the course of executive deficits in late-life schizophrenia is still controversial as it remains unclear whether …

Education as a moderator of the relationship between episodic memory and amyloid load in normal aging

The current study explored whether education, a proxy of cognitive reserve, modifies the association between episodic memory performance and βeta-amyloid load (Aβ), a biomarker of Alzheimer’s disease, in a cohort of cognitively normal elderly adults. …

Sleep does not help relearning declarative memories in older adults

How sleep affects memory in older adults is a critical topic, since age significantly impacts both sleep and memory. For declarative memory, previous research reports contradictory results, with some studies showing sleep-dependent memory …